Changed classifications & opinions put out of force

The following table lists classifications that have changed due to current data. For more detailed information, please call up the corresponding entry in the respective database via the link. Statements that were put out of force are also listed here.

Date of change
Out of force: Opinion of the ZKBS on the categorisation of parasites Leishmania brasiliensis, Leishmania donovani, Plasmodium falciparum and Trypanosoma brucei rhodesiense as recipient organisms in genetic engineering work (Az. 6790-10-70, 2021)The Statement is replaced by the Statement of the ZKBS on genetic engineering work with parasites (Ref. 08020203.0002.0002, 2024).Jul. 2024
Eubacterium limosum Downgrade to risk group 1Jul. 2024
Cell line Ba/F3Upgrade to risk group 2Mar. 2024
Ralstonia pickettiiUpgrade to risk group 2Jul. 2023
Leuconostoc mesenteroides ssp. mesenteroidesUpgrade to risk group 2May 2023
Cell line SK-DSRCT-1Downgrade to risk group 1Aug. 2022
Cell line SK-DSRCT-2Downgrade to risk group 1Aug. 2022
Cell line NK-92Data from a lymphocyte transformation test were submitted. The cells can therefore still be assigned to risk group 1.Feb. 2022
Statement of the ZKBS on the infection of animals with genetically modified organisms of risk group 2 (Az.: 6790-10-31, 1994)The issues addressed are now adequately addressed in the provisions of the GenTG and GenTSV. The statement has been removed from the homepage.Feb. 2022
Gibco episomal hiPSC LineDowngrade to risk group 1Jul. 2021
Varizella-Zoster-Virus-Impfstamm vOkaDowngrade to risk group 1Feb. 2021
Lymphocytic choriomeningitis virus (LCMV)Downgrade to risk group 2Jul. 2020
Plasmodium knowlesiUpgrade to risk group 3**Jul. 2020
Cell line UKE-1Downgrade to risk group 1Dec. 2019
Trypanosoma brucei gambienseUpgrade to risk group 3**Dec. 2019
Tollwutvirus Impfstamm SPBN GASGASDowngrade to risk group 1 (*)Sep. 2019
Cell line W12Upgrade to risk group 2Aug. 2019
Cell line BLaER1Upgrade to risk group 2Aug. 2019
Zelllinie UPCI:SCC090 (auch SCC090)Upgrade to risk group 2Jul. 2019
Capronia mansonii (teleomorph)Downgrade to risk group 1Apr. 2019
Hortaea werneckiiDowngrade to risk group 1Apr. 2019
Sporothrix stenocerasDowngrade to risk group 1Apr. 2019
Cell line T2 (174 x CEM.T2)Upgrade to risk group 2Mar. 2019


(*) Applies on the condition that the manufacturing conditions specified in the approval are complied with (number of passages, cell cultures used for virus replication).

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